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https://idr.l4.nitk.ac.in/jspui/handle/123456789/13206Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Sankappa, Rai, U. | - |
| dc.contributor.author | Isloor, A.M. | - |
| dc.contributor.author | Shetty, P. | - |
| dc.contributor.author | Isloor, N. | - |
| dc.contributor.author | Malladi, S. | - |
| dc.contributor.author | Fun, H.-K. | - |
| dc.date.accessioned | 2020-03-31T08:45:23Z | - |
| dc.date.available | 2020-03-31T08:45:23Z | - |
| dc.date.issued | 2010 | - |
| dc.identifier.citation | European Journal of Medicinal Chemistry, 2010, Vol.45, 12, pp.6090-6094 | en_US |
| dc.identifier.uri | http://idr.nitk.ac.in/jspui/handle/123456789/13206 | - |
| dc.description.abstract | A three-component Mannich reaction of different ketones with aromatic aldehydes and different amines in microwave irradiation under solvent free condition afforded corresponding ?-amino carbonyl compounds in excellent yields. This method proved as a novel and improved modification of the reported three-component Mannich reaction in terms of milder reaction conditions, reaction times, clean reaction profiles, very small quantity of catalyst and simple workup procedure. Newly synthesized ?-aminoketones were characterized by spectral studies. Structure of compound 4a was also confirmed by single-crystal X-ray analysis. All the compounds were screened for their antimicrobial activity by MIC method. Few of the molecules were found to be biologically potent. 2010 Elsevier Masson SAS. All rights reserved. | en_US |
| dc.title | Synthesis and biological evaluation of aminoketones | en_US |
| dc.type | Article | en_US |
| Appears in Collections: | 1. Journal Articles | |
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